Cleveland, Ohio clinic performs US’s first face transplant

Thursday, December 18, 2008

A team of eight transplant surgeons in Cleveland Clinic in Ohio, USA, led by reconstructive surgeon Dr. Maria Siemionow, age 58, have successfully performed the first almost total face transplant in the US, and the fourth globally, on a woman so horribly disfigured due to trauma, that cost her an eye. Two weeks ago Dr. Siemionow, in a 23-hour marathon surgery, replaced 80 percent of her face, by transplanting or grafting bone, nerve, blood vessels, muscles and skin harvested from a female donor’s cadaver.

The Clinic surgeons, in Wednesday’s news conference, described the details of the transplant but upon request, the team did not publish her name, age and cause of injury nor the donor’s identity. The patient’s family desired the reason for her transplant to remain confidential. The Los Angeles Times reported that the patient “had no upper jaw, nose, cheeks or lower eyelids and was unable to eat, talk, smile, smell or breathe on her own.” The clinic’s dermatology and plastic surgery chair, Francis Papay, described the nine hours phase of the procedure: “We transferred the skin, all the facial muscles in the upper face and mid-face, the upper lip, all of the nose, most of the sinuses around the nose, the upper jaw including the teeth, the facial nerve.” Thereafter, another team spent three hours sewing the woman’s blood vessels to that of the donor’s face to restore blood circulation, making the graft a success.

The New York Times reported that “three partial face transplants have been performed since 2005, two in France and one in China, all using facial tissue from a dead donor with permission from their families.” “Only the forehead, upper eyelids, lower lip, lower teeth and jaw are hers, the rest of her face comes from a cadaver; she could not eat on her own or breathe without a hole in her windpipe. About 77 square inches of tissue were transplanted from the donor,” it further described the details of the medical marvel. The patient, however, must take lifetime immunosuppressive drugs, also called antirejection drugs, which do not guarantee success. The transplant team said that in case of failure, it would replace the part with a skin graft taken from her own body.

Dr. Bohdan Pomahac, a Brigham and Women’s Hospital surgeon praised the recent medical development. “There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Leading bioethicist Arthur Caplan of the University of Pennsylvania withheld judgment on the Cleveland transplant amid grave concerns on the post-operation results. “The biggest ethical problem is dealing with failure — if your face rejects. It would be a living hell. If your face is falling off and you can’t eat and you can’t breathe and you’re suffering in a terrible manner that can’t be reversed, you need to put on the table assistance in dying. There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Dr Alex Clarke, of the Royal Free Hospital had praised the Clinic for its contribution to medicine. “It is a real step forward for people who have severe disfigurement and this operation has been done by a team who have really prepared and worked towards this for a number of years. These transplants have proven that the technical difficulties can be overcome and psychologically the patients are doing well. They have all have reacted positively and have begun to do things they were not able to before. All the things people thought were barriers to this kind of operations have been overcome,” she said.

The first partial face transplant surgery on a living human was performed on Isabelle Dinoire on November 27 2005, when she was 38, by Professor Bernard Devauchelle, assisted by Professor Jean-Michel Dubernard in Amiens, France. Her Labrador dog mauled her in May 2005. A triangle of face tissue including the nose and mouth was taken from a brain-dead female donor and grafted onto the patient. Scientists elsewhere have performed scalp and ear transplants. However, the claim is the first for a mouth and nose transplant. Experts say the mouth and nose are the most difficult parts of the face to transplant.

In 2004, the same Cleveland Clinic, became the first institution to approve this surgery and test it on cadavers. In October 2006, surgeon Peter Butler at London‘s Royal Free Hospital in the UK was given permission by the NHS ethics board to carry out a full face transplant. His team will select four adult patients (children cannot be selected due to concerns over consent), with operations being carried out at six month intervals. In March 2008, the treatment of 30-year-old neurofibromatosis victim Pascal Coler of France ended after having received what his doctors call the worlds first successful full face transplant.

Ethical concerns, psychological impact, problems relating to immunosuppression and consequences of technical failure have prevented teams from performing face transplant operations in the past, even though it has been technically possible to carry out such procedures for years.

Mr Iain Hutchison, of Barts and the London Hospital, warned of several problems with face transplants, such as blood vessels in the donated tissue clotting and immunosuppressants failing or increasing the patient’s risk of cancer. He also pointed out ethical issues with the fact that the procedure requires a “beating heart donor”. The transplant is carried out while the donor is brain dead, but still alive by use of a ventilator.

According to Stephen Wigmore, chair of British Transplantation Society’s ethics committee, it is unknown to what extent facial expressions will function in the long term. He said that it is not certain whether a patient could be left worse off in the case of a face transplant failing.

Mr Michael Earley, a member of the Royal College of Surgeon‘s facial transplantation working party, commented that if successful, the transplant would be “a major breakthrough in facial reconstruction” and “a major step forward for the facially disfigured.”

In Wednesday’s conference, Siemionow said “we know that there are so many patients there in their homes where they are hiding from society because they are afraid to walk to the grocery stores, they are afraid to go the the street.” “Our patient was called names and was humiliated. We very much hope that for this very special group of patients there is a hope that someday they will be able to go comfortably from their houses and enjoy the things we take for granted,” she added.

In response to the medical breakthrough, a British medical group led by Royal Free Hospital’s lead surgeon Dr Peter Butler, said they will finish the world’s first full face transplant within a year. “We hope to make an announcement about a full-face operation in the next 12 months. This latest operation shows how facial transplantation can help a particular group of the most severely facially injured people. These are people who would otherwise live a terrible twilight life, shut away from public gaze,” he said.

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“A commonsense proposal”: Wikinews interviews Michelle Tilley, Campaign Director for Yes on 820

Thursday, January 12, 2023

On March 7, voters in the US state of Oklahoma will decide on State Question 820, the Marijuana Legalization Initiative.

If the initiative passes, adults 21 and older could own up to an ounce (28.35 grams) of recreational marijuana and cultivate “not more than six (6) mature marijuana plants and six (6) seedlings” in their homes, and some convictions for marijuana possession could be expunged. The state’s profits earned by taxing marijuana transactions would fund the Oklahoma Medical Marijuana Authority, while the rest would be split between: the state’s fund pool (30%), programs in public schools to improve student success, extracurricular activities, and decrease drug abuse (30%), governmental and nonprofit programs to counter drug abuse (20%), courts (10%), and the local government where the transaction occurred (10%).

Wikinews emailed interview questions to the Yes campaign on January 6; Michelle Tilley, their Campaign Director, responded on January 11. The following is the interview with Tilley.

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Harvard University officials update Agassiz Neighborhood Council about local construction in Cambridge, Massachusetts

Thursday, April 28, 2005

Cambridge, Massachusetts —Harvard University planners met with the Agassiz Neighborhood Council to update the community about Harvard’s construction and expansion plans in the neighborhood on April 26, the Harvard Crimson reported today. The two major topics discussed were the Northwest Science Building, which is currently under construction on Oxford Street, and the expansion of the Harvard Law School. According to the Crimson, Harvard officials outnumbered the number of community members present at the meeting.

The plans for law school expansion are still unfinished, the Crimson reported. The director of community relations at Harvard, Thomas Lucey, said that Wyeth Hall may be demolished. According to the Law School website, Wyeth Hall is “the most popular dormitory at Harvard Law School”. It is adjacent to the Berkman Center for Internet and Society on Massachusetts Avenue, just south of Three Aces pizzeria.

The Crimson also noted that Tom Murray, the project manager for the Northwest Science Building, was slated for completion by May of 2007, with landscaping completed the following spring.

A visit to the science building site by Wikinews reporter Pingswept last week verified that the pouring of cement had begun. Four large cranes had been brought to the site; one of them was being used with a clamshell attachment twice the height of a grown man to dig a deep trench. The truck “wheel wash” station marked on the site plan was operational, in the form of a man with a pressure washer, though in this reporter’s brief observations, more windshields were washed than dirty tires.

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Victoria Wyndham on Another World and another life

Thursday, December 13, 2007

Victoria Wyndham was one of the most seasoned and accomplished actresses in daytime soap opera television. She played Rachel Cory, the maven of Another World‘s fictional town, Bay City, from 1972 to 1999 when the show went off the air. Wyndham talks about how she was seen as the anchor of a show, and the political infighting to keep it on the air as NBC wanted to wrest control of the long-running soap from Procter & Gamble. Wyndham fought to keep it on the air, but eventually succumbed to the inevitable. She discusses life on the soap opera, and the seven years she spent wandering “in the woods” of Los Angeles seeking direction, now divorced from a character who had come to define her professional career. Happy, healthy and with a family she is proud of, Wyndham has found life after the death of Another World in painting and animals. Below is David Shankbone’s interview with the soap diva.

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Venezuelan President Chavez in Beijing to boost trade

Friday, August 25, 2006

Venezuelan President Hugo Chavez arrived in the Chinese capital of Beijing, Wednesday, beginning a visit that will see new agreements to increase China’s investment in Venezuela’s petroleum, telecoms, agriculture and transport. Chavez says that his country intends to boost its oil exports to China to 500,000 barrels a day within five years, quadrupling its current exports, and up to one million barrels a day by 2012.

“Within five years we’ll arrive at half a million barrels (a day) to China. We are currently exporting close to 150,000 barrels (a day), and next year we will double that,” Chavez said.

“The oil issue is of utmost importance because we are diversifying the petroleum business. We are moving toward a new petroleum model,” said Chavez, speaking on Venezuelan state television from China. “It’s one step more in a strategic alliance.”

Chavez met Chinese President Hu Jintao on Thursday, senior leader Wu Bangguo and Premier Wen Jiabao on Friday. Following Thursday’s meeting, Chavez said that Jintao agreed to support Venezuela’s bid to join the United Nations Security Council as a non-permanent member. He is also discussing Chinese involvement in developing his countries gold and coal mining industries, according to reports.

The countries are also signing agreements for Chinese assistance in building a petrochemical plant within the Amuay oil refinery in western Venezuela.

Agreements are expected to be signed with two of China’s state owned oil companies to develop and export crude from Venezuela’s Orinoco river basin as well as to approve the sale of Chinese oil tankers to Venezuela.

While the United States remains the leading importer of Venezuela’s oil, Chavez’ left wing government has sought to diversify its trading partners in an attempt to reduce its reliance on the United States and promote a “multi-polar” world order.

China is the world’s second largest consumer of petroleum and is in need of increased oil supplies in order to maintain its rapid pace of economic growth.

Chavez told Venezuelan state television that increased trade with China and Russia will help boost Venezuela to medium-power status. He claimed that investment agreements with China will transfer technology to his country and help Venezuela escape dependency.

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Minnesota oil pipeline explosion and fire kills two

Friday, November 30, 2007

A major oil pipeline in Minnesota exploded and caught fire, killing two workers. The pipeline carries oil from Saskatchewan, Canada to close to Chicago, United States, representing 16% of America’s total oil imports.

The section of the pipe that exploded was undergoing maintenance at the time to address a pinhole leak first identified three weeks earlier, and patched at the time with a metal sleeve. On Wednesday, the entire section was removed and replaced with a new one. When oil was reintroduced on Thursday morning, oil leaked where the new section joined the pre-existing pipe, triggering the fatal explosion.

The fire was extinguished later the same day.

The line is split between four separate pipes. After the explosion, all four pipes were shut down, resulting in the global price surge, but this subsided for the most part after it became clear that the three undamaged pipelines had returned to normal operation, restoring 80% of the line’s capacity, and that the accident pipe is expected to be back in use in a matter of days.

“There were no problems found in that area where the leak occurred,” reporters were told by Larry Springer, spokesman for Enbridge, the Canadian company that owns the line. High-tech equipment had been through the line in 2006 to check for any signs of problems.

Enbridge identified the deceased as Dave Mussati Jr. and Steve Arnovich, both of whom were contract workers based in Superior, Wisconsin. The damaged section of pipe is in Clearbrook, which is approximately 350 miles Northwest of Minneapolis.

Enbridge metallurgists have been sent to examine the failed section in an effort to determin the cause of the accident. Other Enbridge workers are working to clear spilled oil from the site. It is expected that once this is complete, the pipe will return to service.

Global crude oil prices temporarily spiked by over US$4 per barrel but closed yesterday slightly above original prices.

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With US mid-term elections fast approaching, three prominent Democrats announce retirement

Thursday, January 7, 2010

With this year’s November midterm elections fast approaching, three prominent United States Democrats announced their plans for retirement from public service on Wednesday.

Powerful and influential—yet controversial for his alleged close ties to the financial sector and his handling of last year’s bailout—Senator Christopher Dodd of Connecticut announced that he would not be seeking a sixth term this year.

In a speech to his supporters in East Haddam, Connecticut, the sixty-five-year-old senior senator—with his family at his side—said, “I have been a Connecticut senator for thirty years. I’m very proud of the job I’ve done and the results delivered. But none of us is irreplaceable. None of us is indispensable.”

He then went on to say, “Over the past twelve months, I’ve managed four major pieces of legislation through the United States Congress, served as chair and acting chair of two major Senate committees, placing me at the center of the two most important issues of our time—health care and reform of financial services.”

In addition to highlighting some personal travails, Dodd alluded to his precarious political situation, “I lost a beloved sister in July, and in August, Ted Kennedy. I battled cancer over the summer, and in the midst of all of this, found myself in the toughest political shape of my career.”

Despite this, Dodd adamantly maintained that none of the above reasons were the causes for his retirement. He said that his reasons were more “personal,” and that his retirement would hopefully give him a much-wanted opportunity to spend more time with his family.

Senator Byron Dorgan of North Dakota announced that he would not run for re-election this year either.

“Although I still have a passion for public service and enjoy my work in the Senate, I have other interests and I have other things I would like to pursue outside of public life,” said the sixty-seven-year-old, three-term senator who said he came to this decision after discussing his future with his immediate family over Christmas.

Governor of Colorado, Bill Ritter announced that he too would not seek a second term. The fifty-three-year-old freshman governor said that although he felt his race was “absolutely winnable,” after some deep “soul searching,” he realized that he truly wanted to retire from politics nonetheless. This due to the fact that he felt his main priority should be to be a better husband to his wife as well as a better father to their four children.

When asked to comment on Senator Dodd’s retirement on behalf of the Administration, Vice President Joseph Biden said Dodd would “be long recognized as one of the most significant senators of my generation.”

He furthermore stated, “I believe the nation will miss his wisdom, wit and compassion. I count myself lucky because I know he’s not going too far and will always be a source of advice and counsel.”

Biden gave similar comments and expressed like sentiments about the retirement of his other two Democratic colleagues as well.

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Israel Journal: Is Yossi Vardi a good father to his entrepreneurial children?

Thursday, December 20, 2007

Wikinews reporter David Shankbone is currently, courtesy of the Israeli government and friends, visiting Israel. This is a first-hand account of his experiences and may — as a result — not fully comply with Wikinews’ neutrality policy. Please note this is a journalism experiment for Wikinews and put constructive criticism on the collaboration page.

This article mentions the Wikimedia Foundation, one of its projects, or people related to it. Wikinews is a project of the Wikimedia Foundation.

Dr. Yossi Vardi is known as Israel’s ‘Father of the Entrepreneur’, and he has many children in the form of technology companies he has helped to incubate in Tel Aviv‘s booming Internet sector. At the offices of Superna, one such company, he introduced a whirlwind of presentations from his baby incubators to a group of journalists. What stuck most in my head was when Vardi said, “What is important is not the technology, but the talent.” Perhaps because he repeated this after each young Internet entrepreneur showed us his or her latest creation under Vardi’s tutelage. I had a sense of déjà vu from this mantra. A casual reader of the newspapers during the Dot.com boom will remember a glut of stories that could be called “The Rise of the Failure”; people whose technology companies had collapsed were suddenly hot commodities to start up new companies. This seemingly paradoxical thinking was talked about as new back then; but even Thomas Edison—the Father of Invention—is oft-quoted for saying, “I have not failed. I have just found ten thousand ways that won’t work.”

Vardi’s focus on encouraging his brood of talent regardless of the practicalities stuck out to me because of a recent pair of “dueling studies” The New York Times has printed. These are the sort of studies that confuse parents on how to raise their kids. The first, by Carol Dweck at Stanford University, came to the conclusion that children who are not praised for their efforts, regardless of the outcome’s success, rarely attempt more challenging and complex pursuits. According to Dweck’s study, when a child knows that they will receive praise for being right instead of for tackling difficult problems, even if they fail, they will simply elect to take on easy tasks in which they are assured of finding the solution.

Only one month earlier the Times produced another story for parents to agonize over, this time based on a study from the Brookings Institution, entitled “Are Kids Getting Too Much Praise?” Unlike Dweck’s clinical study, Brookings drew conclusions from statistical data that could be influenced by a variety of factors (since there was no clinical control). The study found American kids are far more confident that they have done well than their Korean counterparts, even when the inverse is true. The Times adds in the words of a Harvard faculty psychologist who intoned, “Self-esteem is based on real accomplishments. It’s all about letting kids shine in a realistic way.” But this is not the first time the self-esteem generation’s proponents have been criticized.

Vardi clearly would find himself encouraged by Dweck’s study, though, based upon how often he seemed to ask us to keep our eyes on the people more than the products. That’s not to say he has not found his latest ICQ, though only time—and consumers—will tell.

For a Web 2.User like myself, I was most fascinated by Fixya, a site that, like Wikipedia, exists on the free work of people with knowledge. Fixya is a tech support site where people who are having problems with equipment ask a question and it is answered by registered “experts.” These experts are the equivalent of Wikipedia’s editors: they are self-ordained purveyors of solutions. But instead of solving a mystery of knowledge a reader has in their head, these experts solve a problem related to something you have bought and do not understand. From baby cribs to cellular phones, over 500,000 products are “supported” on Fixya’s website. The Fixya business model relies upon the good will of its experts to want to help other people through the ever-expanding world of consumer appliances. But it is different from Wikipedia in two important ways. First, Fixya is for-profit. The altruistic exchange of information is somewhat dampened by the knowledge that somebody, somewhere, is profiting from whatever you give. Second, with Wikipedia it is very easy for a person to type in a few sentences about a subject on an article about the Toshiba Satellite laptop, but to answer technical problems a person is experiencing seems like a different realm. But is it? “It’s a beautiful thing. People really want to help other people,” said the presenter, who marveled at the community that has already developed on Fixya. “Another difference from Wikipedia is that we have a premium content version of the site.” Their premium site is where they envision making their money. Customers with a problem will assign a dollar amount based upon how badly they need an answer to a question, and the expert-editors of Fixya will share in the payment for the resolved issue. Like Wikipedia, reputation is paramount to Fixya’s experts. Whereas Wikipedia editors are judged by how they are perceived in the Wiki community, the amount of barnstars they receive and by the value of their contributions, Fixya’s customers rate its experts based upon the usefulness of their advice. The site is currently working on offering extended warranties with some manufacturers, although it was not clear how that would work on a site that functioned on the work of any expert.

Another collaborative effort product presented to us was YouFig, which is software designed to allow a group of people to collaborate on work product. This is not a new idea, although may web-based products have generally fallen flat. The idea is that people who are working on a multi-media project can combine efforts to create a final product. They envision their initial market to be academia, but one could see the product stretching to fields such as law, where large litigation projects with high-level of collaboration on both document creation and media presentation; in business, where software aimed at product development has generally not lived up to its promises; and in the science and engineering fields, where multi-media collaboration is quickly becoming not only the norm, but a necessity.

For the popular consumer market, Superna, whose offices hosted our meeting, demonstrated their cost-saving vision for the Smart Home (SH). Current SH systems require a large, expensive server in order to coordinate all the electronic appliances in today’s air-conditioned, lit and entertainment-saturated house. Such coordinating servers can cost upwards of US$5,000, whereas Superna’s software can turn a US$1,000 hand-held tablet PC into household remote control.

There were a few start-ups where Vardi’s fatherly mentoring seemed more at play than long-term practical business modeling. In the hot market of WiFi products, WeFi is software that will allow groups of users, such as friends, share knowledge about the location of free Internet WiFi access, and also provide codes and keys for certain hot spots, with access provided only to the trusted users within a group. The mock-up that was shown to us had a Google Maps-esque city block that had green points to the known hot spots that are available either for free (such as those owned by good Samaritans who do not secure their WiFi access) or for pay, with access information provided for that location. I saw two long-term problems: first, WiMAX, which is able to provide Internet access to people for miles within its range. There is already discussion all over the Internet as to whether this technology will eventually make WiFi obsolete, negating the need to find “hot spots” for a group of friends. Taiwan is already testing an island-wide WiMAX project. The second problem is if good Samaritans are more easily located, instead of just happened-upon, how many will keep their WiFi access free? It has already become more difficult to find people willing to contribute to free Internet. Even in Tel Aviv, and elsewhere, I have come across several secure wireless users who named their network “Fuck Off” in an in-your-face message to freeloaders.

Another child of Vardi’s that the Brookings Institution might say was over-praised for self-esteem but lacking real accomplishment is AtlasCT, although reportedly Nokia offered to pay US$8.1 million for the software, which they turned down. It is again a map-based software that allows user-generated photographs to be uploaded to personalized street maps that they can share with friends, students, colleagues or whomever else wants to view a person’s slideshow from their vacation to Paris (“Dude, go to the icon over Boulevard Montmartre and you’ll see this girl I thought was hot outside the Hard Rock Cafe!”) Aside from the idea that many people probably have little interest in looking at the photo journey of someone they know (“You can see how I traced the steps of Jesus in the Galilee“), it is also easy to imagine Google coming out with its own freeware that would instantly trump this program. Although one can see an e-classroom in architecture employing such software to allow students to take a walking tour through Rome, its desirability may be limited.

Whether Vardi is a smart parent for his encouragement, or in fact propping up laggards, is something only time will tell him as he attempts to bring these products of his children to market. The look of awe that came across each company’s representative whenever he entered the room provided the answer to the question of Who’s your daddy?

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On the campaign trail in the USA, October 2020

Monday, November 2, 2020

The following is the sixth and final edition of a monthly series chronicling the 2020 United States presidential election. It features original material compiled throughout the previous month after an overview of the month’s biggest stories.

This month’s spotlight on the campaign trail: the Free and Equal Elections Foundation holds two presidential debates, three candidates who did not participate in those debates give their final pleas to voters, and three political pundits give their predictions on the outcome of the election.

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Ted Kennedy diagnosed with brain tumor

Tuesday, May 20, 2008

Senator Ted Kennedy, a Democrat from Massachusetts, who was recently hospitalized after suffering two seizures, has been diagnosed with a malignant brain tumor. Kennedy’s doctors discovered the tumor as part of a battery of tests performed to diagnose the cause of the seizures.

Late last week the senator was rushed to Cape Cod Hospital from the Kennedy Compound, after reportedly suffering stroke-like symptoms. After two hours in the emergency room, he was flown to Massachusetts General Hospital in Boston, Massachusetts.

A statement given by Dr. Lee Schwamm and Dr. Larry Ronan of Massachusetts General Hospital stated, “Over the course of the last several days, we’ve done a series of tests on Senator Kennedy to determine the cause of his seizure. He has had no further seizures, remains in good overall condition, and is up and walking around the hospital.”

The statement went on to say, “However, preliminary results from a biopsy of the brain identified the cause of the seizure as a malignant glioma in the left parietal lobe. The usual course of treatment includes combinations of various forms of radiation and chemotherapy.”

The statement finished by saying, “Decisions regarding the best course of treatment for Senator Kennedy will be determined after further testing and analysis. Senator Kennedy will remain at Massachusetts General Hospital for the next couple of days according to routine protocol. He remains in good spirits and full of energy.”

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